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Operations Portal is an EGI service provided by black Rylee 60 leather buckle ankle boots Chlo�� fF4ot9E9
, co-funded by EGI.eu and EGI-Engage

Release Version : 4.2 - October 24th

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Latest news

Decommissionning

Dear beapps users and managers, We will decommission the BEgrid LFC service hosted by lfc01.begrid.be. As this service is not used anymore since years, we will stop it today (6th of July 2018) and it will be removed on Monday 9th of July 2018. Regards, Stéphane Gérard

Decommissioning of EGI site M3PEC

Dear VO users, dear VO managers, We inform you that EGI site M3PEC will be decommissioned along with all its services. All services will be in downtime from 2018/08/03. The decommissioning process will be recorded in the following GGUS ticket: https://ggus.eu/index.php?mode=ticket_infoticket_id=135952 Best regards,

Decommissioning INFN-BOLOGNA-T3

Dear all, The INFN-BOLOGNA-T3 site is starting decommissioning procedure. All VO were alerted and the data on the storage saved. The timeline of the decommission is as follows - The queues of the site have already been closed for months - On 03/07/2018 Start downtime - On 16/07/2018 The site status change to "Closed" in GOCDB All the services that the site is hosting will follow the same timeline plan. The hosted services are : APEL, Site-BDII, Cream-CE, SRM, glEexc, ARGUS. Kind regards, Patrizia Calligola

EGI Trust Anchor release 1.92-1

Dear all, this broadcast was not properly delivered on the 25 of June because a problem in the Broadcast Tool which has been solved this morning. In order to give you the right time for upgrading the CAs packages, we are extending the grace period of the IGTF nagios probe to 7 days starting from now. EUGridPMA have announced a new set of CA rpms. Based on this IGTF release a new set of CA RPMs have been packaged for EGI. This release brings some changes at the level of the meta-pakage names so please read the release notes carefully and upgrade until 2018.07.02 at your earliest convenience. When this timeout is over, SAM will throw critical errors on CA tests if old CAs are still detected. Please check https://wiki.egi.eu/wiki/EGI_IGTF_Release for more details EGI UMD software provisioning Team The following release notes accompany this version: European Grid Infrastructure EGI Trust Anchor release 1.92 2018.06.25 ------------------------------------------------------------------------------ For release DOCUMENTATION available on this EGI Trust Anchor release see https://wiki.egi.eu/wiki/EGI_IGTF_Release ------------------------------------------------------------------------------ This is the EGI Trust Anchor release, based on the updated IGTF Accredited CA distribution version 1.92-1 with the specific DOGWOOD CA in meta-package "ca-policy-egi-combined-adequacy-model-1.92-1" that supports the model of joint assurance provision as detailed in the EGI Policy on Acceptable Authentication Assurance. IMPORTANT NOTICE: This release contains a new "cam" (combined assurance/adequacy) package based on the approved policy on differentiated assurance. See details on the EGI Wiki at https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl TECHNICALLY THIS MEANS THAT you must ONLY install the new ca-policy-egi-cam packages if you ALSO at the same time implement VO-specific authorization controls in your software stack. This may require reconfiguration or a software update. See https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl OTHERWISE just only install or update the regular ca-policy-egi-core package. There are no changes in this case. The ca-policy-egi-core package is approved for all VOs membership and assurance models. No configuration change is needed. With the introduction of combined assurance/adequacy, the EGEE compatibility RPM (lcg-CA) can no longer be supported, and - when still installed - will be obsoleted. The proper dependency packages are: ca-policy-_body_-_class_ and these have been installed automatically as dependencies since 2010. The following notices are republished from the IGTF, inasfar as pertinent to this release. Details are found in the newsletter https://www.eugridpma.org/ Changes from 1.91 to 1.92 ------------------------- (25 Jun 2018) * Added HKU CA 2 trust anchor during transitioning period (HK) The CA modifications encoded in both "requires" and "obsoletes" clauses (RPM) and Conflicts/Replaced clauses (Debian) have been incorporated in the above- mentioned meta-packages. This release is best enjoyed with fetch-crl v3 or better, available from GNU/Linux OS add-on repositories Fedora, EPEL, Debian, and from the IGTF at https://www.igtf.net/fetch-crl Policy on Acceptable Authentication Assurance (Updated 1 Feb 2017) ------------------------------------------------------------------ If a VO registration service or e-Infrastructure registration service is accredited by EGI to meet or exceed the approved authentication assurance profiles, an IGTF accredited Authority meeting the Assurance Profile DOGWOOD - used solely in combination with said registration service - is also adequate for user authentication. This policy has been adopted on Feb 1st, 2017, and is available at https://documents.egi.eu/document/2930 In the PKI Technology Rendering, EGI thus approves the IGTF SLCS, MICS, and Classic APs for general use (egi-core), and in addition the IOTA AP for use in combination with VO registration services that themselves meet the aforementioned requirements. This additional restriction must be implemented by each service in the authorization software. The "combined assurance" model package must not be installed unless the additional authorization is in place. You will need to reconfigure and may need to install upgrades. Version information: ca-policy-egi-combined-adequacy-model = 1.92-1

EGI Trust Anchor release 1.92-1

Dear all, EUGridPMA have announced a new set of CA rpms. Based on this IGTF release a new set of CA RPMs have been packaged for EGI. This release brings some changes at the level of the meta-pakage names so please read the release notes carefully and upgrade until 2018.07.02 at your earliest convenience. When this timeout is over, SAM will throw critical errors on CA tests if old CAs are still detected. Please check https://wiki.egi.eu/wiki/EGI_IGTF_Release for more details EGI UMD software provisioning Team The following release notes accompany this version: European Grid Infrastructure EGI Trust Anchor release 1.92 2018.06.25 ------------------------------------------------------------------------------ For release DOCUMENTATION available on this EGI Trust Anchor release see https://wiki.egi.eu/wiki/EGI_IGTF_Release ------------------------------------------------------------------------------ This is the EGI Trust Anchor release, based on the updated IGTF Accredited CA distribution version 1.92-1 with the specific DOGWOOD CA in meta-package "ca-policy-egi-combined-adequacy-model-1.92-1" that supports the model of joint assurance provision as detailed in the EGI Policy on Acceptable Authentication Assurance. IMPORTANT NOTICE: This release contains a new "cam" (combined assurance/adequacy) package based on the approved policy on differentiated assurance. See details on the EGI Wiki at https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl TECHNICALLY THIS MEANS THAT you must ONLY install the new ca-policy-egi-cam packages if you ALSO at the same time implement VO-specific authorization controls in your software stack. This may require reconfiguration or a software update. See https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl OTHERWISE just only install or update the regular ca-policy-egi-core package. There are no changes in this case. The ca-policy-egi-core package is approved for all VOs membership and assurance models. No configuration change is needed. With the introduction of combined assurance/adequacy, the EGEE compatibility RPM (lcg-CA) can no longer be supported, and - when still installed - will be obsoleted. The proper dependency packages are: ca-policy-_body_-_class_ and these have been installed automatically as dependencies since 2010. The following notices are republished from the IGTF, inasfar as pertinent to this release. Details are found in the newsletter https://www.eugridpma.org/ Changes from 1.91 to 1.92 ------------------------- (25 Jun 2018) * Added HKU CA 2 trust anchor during transitioning period (HK) The CA modifications encoded in both "requires" and "obsoletes" clauses (RPM) and Conflicts/Replaced clauses (Debian) have been incorporated in the above- mentioned meta-packages. This release is best enjoyed with fetch-crl v3 or better, available from GNU/Linux OS add-on repositories Fedora, EPEL, Debian, and from the IGTF at https://www.igtf.net/fetch-crl Policy on Acceptable Authentication Assurance (Updated 1 Feb 2017) ------------------------------------------------------------------ If a VO registration service or e-Infrastructure registration service is accredited by EGI to meet or exceed the approved authentication assurance profiles, an IGTF accredited Authority meeting the Assurance Profile DOGWOOD - used solely in combination with said registration service - is also adequate for user authentication. This policy has been adopted on Feb 1st, 2017, and is available at https://documents.egi.eu/document/2930 In the PKI Technology Rendering, EGI thus approves the IGTF SLCS, MICS, and Classic APs for general use (egi-core), and in addition the IOTA AP for use in combination with VO registration services that themselves meet the aforementioned requirements. This additional restriction must be implemented by each service in the authorization software. The "combined assurance" model package must not be installed unless the additional authorization is in place. You will need to reconfigure and may need to install upgrades. Version information: ca-policy-egi-combined-adequacy-model = 1.92-1

EGI Trust Anchor release 1.92-1

Dear all, Apparently this broadcast was not properly delivered on the 25 of June so I would ask all sites to upgrade the CA the fastest way possible. Availability and Reliability will be taken care if errors show up. Sorry for the inconvenient. Previous broadcast was the following: https://operations-portal.egi.eu/broadcast/send/2102 EUGridPMA have announced a new set of CA rpms. Based on this IGTF release a new set of CA RPMs have been packaged for EGI. This release brings some changes at the level of the meta-pakage names so please read the release notes carefully and upgrade until 2018.07.02 at your earliest convenience. When this timeout is over, SAM will throw critical errors on CA tests if old CAs are still detected. Please check https://wiki.egi.eu/wiki/EGI_IGTF_Release for more details EGI UMD software provisioning Team The following release notes accompany this version: European Grid Infrastructure EGI Trust Anchor release 1.92 2018.06.25 ------------------------------------------------------------------------------ For release DOCUMENTATION available on this EGI Trust Anchor release see https://wiki.egi.eu/wiki/EGI_IGTF_Release ------------------------------------------------------------------------------ This is the EGI Trust Anchor release, based on the updated IGTF Accredited CA distribution version 1.92-1 with the specific DOGWOOD CA in meta-package "ca-policy-egi-combined-adequacy-model-1.92-1" that supports the model of joint assurance provision as detailed in the EGI Policy on Acceptable Authentication Assurance. IMPORTANT NOTICE: This release contains a new "cam" (combined assurance/adequacy) package based on the approved policy on differentiated assurance. See details on the EGI Wiki at https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl TECHNICALLY THIS MEANS THAT you must ONLY install the new ca-policy-egi-cam packages if you ALSO at the same time implement VO-specific authorization controls in your software stack. This may require reconfiguration or a software update. See https://wiki.egi.eu/wiki/EGI_IGTF_Release#cam-impl OTHERWISE just only install or update the regular ca-policy-egi-core package. There are no changes in this case. The ca-policy-egi-core package is approved for all VOs membership and assurance models. No configuration change is needed. With the introduction of combined assurance/adequacy, the EGEE compatibility RPM (lcg-CA) can no longer be supported, and - when still installed - will be obsoleted. The proper dependency packages are: ca-policy-_body_-_class_ and these have been installed automatically as dependencies since 2010. The following notices are republished from the IGTF, inasfar as pertinent to this release. Details are found in the newsletter https://www.eugridpma.org/ Changes from 1.91 to 1.92 ------------------------- (25 Jun 2018) * Added HKU CA 2 trust anchor during transitioning period (HK) The CA modifications encoded in both "requires" and "obsoletes" clauses (RPM) and Conflicts/Replaced clauses (Debian) have been incorporated in the above- mentioned meta-packages. This release is best enjoyed with fetch-crl v3 or better, available from GNU/Linux OS add-on repositories Fedora, EPEL, Debian, and from the IGTF at https://www.igtf.net/fetch-crl Policy on Acceptable Authentication Assurance (Updated 1 Feb 2017) ------------------------------------------------------------------ If a VO registration service or e-Infrastructure registration service is accredited by EGI to meet or exceed the approved authentication assurance profiles, an IGTF accredited Authority meeting the Assurance Profile DOGWOOD - used solely in combination with said registration service - is also adequate for user authentication. This policy has been adopted on Feb 1st, 2017, and is available at https://documents.egi.eu/document/2930 In the PKI Technology Rendering, EGI thus approves the IGTF SLCS, MICS, and Classic APs for general use (egi-core), and in addition the IOTA AP for use in combination with VO registration services that themselves meet the aforementioned requirements. This additional restriction must be implemented by each service in the authorization software. The "combined assurance" model package must not be installed unless the additional authorization is in place. You will need to reconfigure and may need to install upgrades. Version information: ca-policy-egi-combined-adequacy-model = 1.92-1

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Tipple Hill Winery Vineyard- Music
Saturday, May 27, 2017 - 7:00pm to 9:30pm
Tipple Hill Winery

Music by Black Top Road playing red dirt country

Stone Hill Winery Sip n' String
Saturday, June 3, 2017 - 11:00am to 1:00pm
Stone Hill Winery

Join us for a day of crafting while sipping wine!Allsupplies and instruction included.Over 30 templates to choose from!Pre-purchased tickets are required for this event.Check in begins at 10:30a.m., event is from 11:00 a.m. to 1:00 p.m.

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Stone Hill Winery Live Music
Saturday, June 3, 2017 - 12:00pm to 4:00pm
Stone Hill Winery

Live music performed by Two for the Road

Event URL: www.stonehillwinery.com

Riverwood Winery Live Music with
Saturday, June 3, 2017 - 1:00pm to 4:00pm
Riverwood Winery

Gather your friends and family to come relax in our auditorium or outdoorpatio (weather permitting) as we welcome local artist, Frank Rardon.Frankuses his songs, his voice and his guitar to share stories of love, family, and personal life experiences to provide for an entertaining afternoon.We’ll have wine, whiskey, and beer as well as delectable cheeses andsalamis available for purchase. No reservations are required to join, justcome uncork with live tunes and wine! No outside alcoholic beverages allowed.

Stone Hill Winery Grapes to Glass
Saturday, June 3, 2017 - 2:30pm to 4:30pm
Stone Hill Winery

A special VIP winery tour and tasting. A member of ourstaff will lead you on a behind the scenes visit to our Norton vineyard,cellars, tank building, and press house, where you’ll learn a bit of thetechnical side and a few of the secrets to our wine making success. Reservations required; limited space. Purchase tickets in advance. Event website

Independence Square Wine and Brew Walk
Friday, June 9, 2017 - 8:00am to 9:00pm
Independence Square

Please join us on June 9th, from 6-9pm for our 6th Annual Wine Brew Walkfundraising event.This event just keeps growing and growing, year afteryear.This is a fundraiser for the preservation and beautification of theHistoric Independence Square.

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Columbia University Medical Center

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January 30, 2018

Pictured above, Adolfo Ferrando (left), professor of pediatrics and of pathology and cell biology at Columbia, with Luis Arnes, associate research scientist and first-place winner of the symposium's poster competition; For photos from the symposium, visit the gallery page . Credit: Lydia Lee Photography

A multidisciplinary team of researchers across Columbia University have been busy addressing the complex challenges in basic and translational cancer research. Faculty and investigators are bridging their expertise in fields ranging from mathematics, biology, and engineering to physics, genomics, and chemistry to develop innovative approaches to better understand, for instance, cancer disease progression, drug resistance, and the systems-wide network of tumor evolution.

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December 5, 2017

Research scientist Hai Li holds up a 384-well plate, pictured in front of Columbia Genome Center's Hamilton Star automation system for HTS; Image credit: Systems Biology

Drug screening and analysis is critical in advancing research and discovery of cancer therapeutics. To this end, a Systems Biology-led team of investigators has recently developed PLATE-Seq, a new technique for low-cost, bulk mRNA sequencing. Coupled with genome-wide regulatory network analysis, the novel PLATE-Seq method advances the goal of providing cancer patients with personalized treatment.

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May 1, 2017

Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. Rooted in the mathematical field of topology, the tool provides a roadmap that offers detailed insight into how stem cells give rise to specialized cells.

The study was published May 1st in Nature Biotechnology.

Every organism begins with one cell. As that cell divides, its copies branch off to become specialized cells—such as heart, bone, or brain cells—in a process known as differentiation. To understand the internal and external cues that move cells along this path, scientists can sequence their RNA—the molecular messenger that translates DNA into proteins and other products.

Sequencing RNA from a batch of cells is not ideal, however, because the cells are usually in different states of development. To address this problem, scientists have developed single-cell RNA sequencing. “It’s like a new microscope, giving us the ability to study many biological phenomena at once,” said Raul Rabadan, PhD , associate professor of systems biology and biomedical informatics at Columbia and co-author of the paper. “However, researchers are still left with the problem of understanding the relationships between different cell states, which drive the process of development.”

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May 21, 2015

The Columbia University Center for Topology of Cancer Evolution and Heterogeneity will combine mathematical approaches from topological data analysis with new single-cell experimental technologies to study cellular diversity in solid tumors. Image courtesy of Raul Rabadan.

The National Cancer Institute’s Physical Sciences in Oncology program has announced the creation of a new center for research and education based at Columbia University. The Center for Topology of Cancer Evolution and Heterogeneity will develop and utilize innovative mathematical and experimental techniques to explore how genetic diversity emerges in the cells that make up solid tumors. In this way it will address a key challenge facing cancer research in the age of precision medicine — how to identify the clonal variants within a tumor that are responsible for its growth, spread, and resistance to therapy. Ultimately, the strategies the Center develops could be used to identify more effective biomarkers of disease and new therapeutic strategies.

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. Founded in 2009, the Network was created to support research that integrates perspectives from the fields of physics, mathematics, chemistry, and engineering in ways that address key questions and obstacles in cancer research.

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